Sergio Moreno
Our group is interested in the regulation of DNA recombination and chromosome segregation during the mitotic and the meiotic cell cycle. In particular, we have recently identified new genes involved in (1) the repair of double strand breaks (DSBs) and in (2) the generation of DSBs in meiosis. In addition, (3) we have generated mouse models with conditional knock out alleles for CDC20 or CDH1 (two activators of the Anaphase Promoting Complex or Cyclosome - APC/C) and are studying the role of these proteins in chromosome stability, cell cycle exit and cell differentiation.

Our main objectives are:
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